SMiles Informatics
Immunoinformatics & Vaccine Design
An emerging research group, leaded by PhD. Sebastian Miles, that focuses on vaccine design by reverse vaccinology. Currently we are working on developing new immunoinformatic algorithms that helps the discovery of new antigens.
About SMiles Informatics
Immunoinformatics & Vaccine Design
SMiles Informatics is a research group focused on the intersection of immunoinformatics and rational vaccine design. It is led by Dr. Sebastián Miles, whose PhD work involved the development of a preclinical peptide vaccine against cystic echinococcosis—a parasitic disease caused by Echinococcus granulosus.
Throughout his academic career, Dr. Miles has explored parasite biology, antigen discovery, reverse vaccinology, and in silico vaccine design. He is currently a postdoctoral researcher at the Biotechnology Department of the University of the Republic (UdelaR, Uruguay), where he focuses on vaccine development and the creation of immunoinformatics tools to aid in antigen selection and design.
At SMiles Informatics, our current projects include the development of vaccines against bovine ticks (Rhipicephalus microplus), Bovine Viral Diarrhea Virus (BVDV), and E. granulosus. We are also pioneering the concept of Synthetic Mimic Proteins (SMPs)—engineered proteins designed to serve as novel and effective vaccine candidates.
Explore Our Predictors
Currently, we only have IApred available, an open-source host-and-pathogen agnostic antigenicity predictor that has been shown to be a balanced, accurate, and accessible alternative to existing antigenicity predictors
Discover Our Predictors